Most Popular Couples On Grey's Anatomy

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14. Izzie Stevens and George O'Malley

13. Alex Karev and April Kepner

12. Izzie Stevens and Denny Duquette

11. Meredith Grey and Finn Dandridge

10. George O'Malley and Callie Tores

9. Jackson Avery and April Kepner

8. Cristina Yang and Preston Burke

7. Callie Torres and Arizona Robbins

6. Mark Sloan and Lexie Grey

5. Miranda Bailey and Ben Warren

4. Alex Karev and Jo Wilson

3. Alex Karev and Izzie Stevens

2. Cristina Yang and Owen Hunt

1. Meredith Grey and Derek Shepherd

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