Grey's Anatomy

15 Biggest Celebrity Guest Stars To Appear On Grey’s Anatomy

Many great guests have been throughout the seasons, but these are the biggest Grey’s Anatomy guest stars.

Grey’s Anatomy

1. Geena Davis

Geena-Davis-in-Greys-Anatomy

2. Keke Palmer

Keke-Palmers-character-Sheryll-Jefferies-in-Greys-Anatomy

3. Abigail Breslin

Keke-Palmers-character-Sheryll-Jefferies-in-Greys-Anatomy

4. John Cho

greys-anatomy-john-cho

5. Elisabeth Moss

Elisabeth-Moss-in-Greys-Anatomy

6. Loretta Devine

Loretta-Devine-Greys-Anatomy

7. Demi Lovato

Demi-Lovato-Greys-Anatomy

8. Mandy Moore

mandy-moore-greys-anatomy-Cropped

9. Christina Ricci

Christina-Ricci-greys-anatomy

10. Leslie Odom Jr.

Leslie-Odom-Jr.-in-Greys-Anatomy

11. Sarah Paulson

Sarah-Paulson-in-Greys-Anatomy

12. Alyssa Milano & Holly Marie Combs

Alyssa-Milano-Holly-Marie-Combs-Greys-Anatomy

13. Tessa Thompson

tessa-thompson-greys-anatomy

14. Kyle Chandler

Dylan-Young-Greys-Anatomy

15. Millie Bobby Brown

Millie-Bobby-Brown-in-Greys-Anatomy

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